A winter storm with roots in the Deep South will slide up the East Coast just as the busiest travel day of the year gets underway Wednesday. The storm will impact all major highways, air travel and transportation by train. Low pressure developing along a stationary front in the eastern Gulf of Mexico is allowing rain to expand in coverage across the Southeast while storms rumble across northern Florida. The low pressure will continue to slide north and northeast, tracking parallel to the coast tonight and Wednesday while a second low pressure dives south from the northern Plains. South and east of the cold front and low pressure, a few potent thunderstorms will slide across central Florida. Gusty winds in excess of 57 mph and a brief tornado are possible in places like Tampa, Orlando and Melbourne. Heavy rain will climb the Interstate 95 corridor today and tonight, with a rain and snow mix likely in the colder air across western North Carolina. As cold air bleeds south, rain and snow will become all snow in places like Asheville and Boone, N.C., with accumulation reaching 3 to 5 inches in the highest elevations. Rain will overspread the Mid-Atlantic before daybreak and change to all snow from Washington`s western suburbs to Interstate 95 as the morning unfolds. Snow will continue through mid-afternoon before tapering off. A slushy inch or two could fall along Interstate 95 with totals reaching 6 to 8 inches in the Blue Ridge mountains east of Interstate 81. The lower elevations will likely end up with 2 to 5 inches before the storm departs Wednesday afternoon. The low pressure will join forces with the northern Plains disturbance later in the day to form a stronger coastal storm in New England. Rain will spread up Interstate 95 to New York by sunrise and then into New England as the morning unfolds. While snow falls in the interior, rain will mix with and change to snow for the major Interstate 95 cities by evening. Snow will then continue into early Thursday, tapering off prior to midday on Thanksgiving for most of New England. When it`s all set and done, 2 to 5 inches will cause slippery travel into and out of New York City with up to 2 inches in Providence, R.I. and Boston. The bull`s eye for snow with this storm will be northeastern Pennsylvania into western Massachusetts, southern and central Vermont and New Hampshire and central and northern Maine. Here, a foot or more will make plows work overtime to clear streets. Winter Storm Warnings and Watches and Winter Weather Advisories stretch from western North Carolina into northern Maine. Baltimore, Philadelphia, New York City, Hartford, Conn., Boston and Providence, R.I., Albany, N.Y., and Portland, Maine are included. A bit of coastal flooding is also likely from Delaware to eastern Massachusetts with the onshore flow expected around the low pressure. High Wind Watches have been hoisted on Cape Cod in Massachusetts where gusts will reach 55 mph for the second half of Wednesday. The winter storm will likely make holiday travel Wednesday a mess across the East. Most of the major airport hubs will likely see delays and cancellations. Although main thoroughfares will likely stay wet, side roads off Interstates 70, 80, 81 and 90 will become slippery. You are urged to leave for your holiday destination today or very early Wednesday before the storm arrives. Check with your airline for the latest cancellation and rebooking information, and check for the latest travel information around the U.S. with WeatherBug`s travel outlook . Be sure to keep WeatherBug active to receive the latest weather in your neighborhood and get the latest updates anywhere on Twitter. What do you think of this story? Click here for comments or suggestions.